WebFeb 23, 2024 · Comparative analysis of metabolic profiles in wild-type and mutant strains is widely used to identify the cryptic metabolites of interest. Inactivation of major secondary metabolite gene cluster (s) sometimes improves the metabolic titer of other metabolites expressed poorly or silent (Fig. 2 a). WebJul 20, 2024 · Untargeted metabolomics using liquid chromatography coupled with tandem mass spectrometry is an efficient technique to access metabolites from fractions and even environmental crude extracts. Nevertheless, metabolomics is limited in predicting structures or bioactivities for cryptic metabolites.
Exploring the roles of fungal-derived secondary metabolites in …
WebDive into the research topics of 'Momomycin, an Antiproliferative Cryptic Metabolite from the Oxytetracycline Producer Streptomyces rimosus'. Together they form a unique fingerprint. Streptomyces rimosus Medicine & Life Sciences 100% WebFeb 3, 2024 · The fungus Aspergillus ochraceus was isolated from the Mediterranean sponge Agelas oroides. The initial fermentation of the fungus on solid rice medium yielded 16 known compounds (4–19). The addition of several inorganic salts to the rice medium mainly influenced the accumulation of these secondary metabolites. … ipg global sourcing
Current strategies to induce secondary metabolites from microbial
WebJul 6, 2016 · As bacteria and fungi have been found to contain genes encoding enzymes that synthesize a plethora of potential secondary metabolites, interest has grown in the activation of these cryptic … WebJun 5, 2024 · ARC2 also altered the secondary metabolome of S. pristinaespiralis, S. Peucetius, and Kutzneria sp. by inducing cryptic metabolites. Recently, Cl-ARC … WebSep 22, 2014 · The term “cryptome” refers to the subset of cryptic peptides with bioactivities that are often unpredictable and very different from the parent protein. These cryptic … ipg group.com