WebDesign, setting, and participants: The HORRAD trial is a multicentre RCT recruiting 432 patients with prostate-specific antigen (PSA) >20 ng/ml and primary bone mPCa on … Web21 okt. 2024 · Parker and colleagues concluded that radiotherapy should be an option for men with newly diagnosed metastatic prostate cancer and a low metastatic burden. A …
Effect on Survival of Androgen Deprivation Therapy Alone …
Web1 jul. 2024 · In HORRAD, planned prostate radiotherapy was initially 70 Gy in 35 fractions over 7 wk (82%), with an alternative schedule of 57.76 Gy in 19 fractions over 6 wk … WebSan Francisco, CA USA (UroToday.com) Herein, we report on the first presentation of the HORRAD trial – the first multi-center randomized controlled trial looking at the role of treatment of the primary prostate cancer malignancy in the setting of metastatic disease – to date, no other trials have reported on this clinical disease space. how tall is a standard handrail
European Urology Vol 75, Issue 3, Pages e43-e84, 355-540 …
Web19 jun. 2024 · Reacties. Recentelijk werd voor het eerst bewijs geleverd dat met louter een lokale behandeling van een maligne prostaattumor de overleving van patiënten met een beperkt gemetastaseerde ziekte verbeterd kan worden. 1 Dit resultaat kwam van de STAMPEDE-trial en is bijzonder relevant, omdat het ingaat tegen een lang bestaande … Web1 mrt. 2024 · The HORRAD trial is a multicentre RCT recruiting 432 patients with prostate-specific antigen (PSA) >20 Outcome measurements and statistical analysis Results and limitations Median PSA level was 142 p = 0.4). No significant difference was found in overall survival (hazard ratio [HR]: 0.90; 95% CI: 0.70–1.14; p = 0.4). WebThe HORRAD trial showed a similar but nonsignificant trend towards RT (hazard ratio 0.68; 95% CI 0.42-1.10). As a result, the 2024 European Association of Urology and National Comprehensive Cancer Network guidelines now include RT to the prostate as an option in the setting of low-volume metastatic disease. how tall is a standard kitchen counter